TY - CHAP M1 - Book, Section TI - Acquired Heart Disease A1 - Okada, Shoichi A1 - Robertson, Jason O. A1 - Saint, Lindsey L. A1 - Damiano, Ralph J. A2 - Brunicardi, F. Charles A2 - Andersen, Dana K. A2 - Billiar, Timothy R. A2 - Dunn, David L. A2 - Hunter, John G. A2 - Matthews, Jeffrey B. A2 - Pollock, Raphael E. PY - 2015 T2 - Schwartz's Principles of Surgery, 10e AB - Although advances have been made in percutaneous coronary intervention techniques for coronary artery disease, survival is superior with coronary artery bypass grafting in patients with left main disease, multivessel disease, and in diabetic patients.Coronary artery bypass grafting has become increasingly safe, and improves late mortality in patients with left main or proximal left anterior descending disease, multivessel disease, and in patients with diabetes.Despite the theoretical advantages, the superiority of off-pump coronary artery bypass to conventional coronary artery bypass grafting has not been clearly established and other factors likely dominate the overall outcome for either technique.Although mechanical valves offer enhanced durability over tissue valve prosthesis, they require permanent systemic anticoagulation therapy to mitigate the risk of valve thrombosis and thromboembolic sequelae, and thus are associated with an increased risk of hemorrhagic complications.Mitral valve repair is recommended over mitral valve replacement in the majority of patients with severe chronic mitral regurgitation. The decision to proceed with mitral valve repair is based on the skill and experience of the surgeon in performing repair, and on the location and type of mitral valve disease encountered at the time of operation.Although open aortic valve replacement has traditionally been the only effective treatment in patients with severe calcific aortic stenosis, transcatheter aortic valve replacement is a developing technology that has proven beneficial for the treatment of aortic stenosis in seriously ill patients that had previously been deemed high risk or inoperable.Mechanical circulatory support with newer generation continuous flow left ventricular assist devices has proven to be durable and effective both in bridging patients to transplant and as a means of “destination therapy” for patients who are not transplant candidates. Recent results for destination therapy have approached those of cardiac transplantation.Performing a biatrial Cox-Maze lesion set results in freedom from atrial fibrillation in approximately 90% of patients and is superior to both catheter-ablation and more limited lesion sets for patients with persistent atrial fibrillation or enlarged left atria. Surgical ablation of atrial fibrillation is recommended for patients referred with concomitant valvular disease and those who have previously failed or are poor candidates for catheter-based approaches.The preferred treatment for pericarditis depends on the underlying cause, although the disease typically follows a self-limited course and is best managed medically. Surgical pericardiectomy may have a role in treating relapsing pericarditis and, more commonly, chronic constrictive pericarditis.Myxomas are the most common cardiac tumors, and, while benign, they should be promptly excised after diagnosis due to the risk of embolization, obstructive complications, and arrhythmias. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1117745985 ER -