TY - CHAP M1 - Book, Section TI - Chapter 3. Pathology of the Immune System A1 - Kemp, Walter L. A1 - Burns, Dennis K. A1 - Brown, Travis G. PY - 2008 T2 - Pathology: The Big Picture AB - Diseases of the immune system take many forms, including hypersensitivity reactions, autoimmune disorders, and immunodeficiency states. Hypersensitivity reactions occur as one of four types (types I–IV). Autoimmune diseases are the result of a failure in the immune system to recognize self-antigens, resulting in production of antibodies that react against normal components of cells. Most of the autoimmune diseases are associated with one or more specific antibodies, which can be identified by laboratory tests to aid in diagnosis. Immunodeficiency states can be hereditary or acquired. A major cause of acquired immunodeficiency is human immunodeficiency virus (HIV) infection. The concepts of immunity are also important in regard to transplantation efforts. This chapter will discuss hypersensitivity reactions, transplantation pathology, autoimmune diseases, amyloidosis, and both hereditary and acquired immunodeficiency. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/29 UR - accessmedicine.mhmedical.com/content.aspx?aid=57050729 ER -