TY - CHAP M1 - Book, Section TI - Chapter 50. Antimicrobial Prophylaxis in Surgery A1 - Anaya, Daniel A. A1 - Dellinger, E. Patchen A2 - McKean, Sylvia C. A2 - Ross, John J. A2 - Dressler, Daniel D. A2 - Brotman, Daniel J. A2 - Ginsberg, Jeffrey S. PY - 2012 T2 - Principles and Practice of Hospital Medicine AB - Surgical site infection (SSI) is the most common complication in surgical patients. Significant advances have occurred over the last few decades resulting in better understanding of the relevant risk factors for SSI, and high-level evidence has identified specific preventive strategies that help reduce the incidence of SSI. With the introduction of asepsis and antisepsis, prophylactic antibiotics have had the most significant impact reducing the incidence of SSI. However, in order to achieve the benefits derived from their use and minimize potential undesired effects, practice of this strategy needs to follow specific basic principles. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=56194452 ER -