TY  - CHAP
M1  - Book, Section
TI  - Chapter 186. Leprosy
A1  - Lee, Delphine J.
A1  - Rea, Thomas H.
A1  - Modlin, Robert L.
A2  - Goldsmith, Lowell A.
A2  - Katz, Stephen I.
A2  - Gilchrest, Barbara A.
A2  - Paller, Amy S.
A2  - Leffell, David J.
A2  - Wolff, Klaus
PY  - 2012
T2  - Fitzpatrick's Dermatology in General Medicine, 8e
AB  - |PrintLeprosy  at  a  GlanceDefinition:  a  chronic  granulomatous  infection  and  caused  by  M.  leprae.Involvement:  affecting  primarily  skin  and  nerves.Diagnosis:  acid-fast  bacilli  in  tissue  or  classic  peripheral  nerve  abnormality.Incidence:  approximately  250,000–500,000  new  cases  yearly,  worldwide.Long-term  morbidity:  despite  curative  antibacterial  treatment,  one-quarter  to  one-third  of  patients  will  have  a  debilitating  and  permanent  neurological  deficit.A  clinical  challenge:  diverse  manifestations  result  from  a  granulomatous  spectrum,  and  are  further  increased  by  superimposed,  reactional  states.An  immunologic  opportunity:  an  exemplary  model  for  the  understanding  of  cell-mediated  immunity  in  humans.  
SN  - 
PB  - The McGraw-Hill Companies
CY  - New York, NY
Y2  - 2024/04/18
UR  - accessmedicine.mhmedical.com/content.aspx?aid=56084826
ER  -