TY - CHAP M1 - Book, Section TI - Chapter 173. Cutaneous Changes in Peripheral Arterial Vascular Disease A1 - Chadachan, Veerendra A1 - Dean, Steven M. A1 - Eberhardt, Robert T. A2 - Goldsmith, Lowell A. A2 - Katz, Stephen I. A2 - Gilchrest, Barbara A. A2 - Paller, Amy S. A2 - Leffell, David J. A2 - Wolff, Klaus PY - 2012 T2 - Fitzpatrick's Dermatology in General Medicine, 8e AB - |PrintObstructive Peripheral Arterial Disease at a GlanceMost commonly due to atherosclerosis of the vessels supplying the lower extremity.Affects 15% of the US adult population over the age of 65 years.Stenosis or obstruction of the large arteries to the lower extremities leading to supply demand mismatch, initially with exertion but may progress to occur at rest.Intermittent claudication with exertional muscle pain or fatigue, critical limb ischemia with rest pain or tissue compromise, and acute limb ischemia.Cutaneous findings from hypoperfusion ranging from dry skin, hair loss, and malformed toenails to ulceration and gangrene. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/11/03 UR - accessmedicine.mhmedical.com/content.aspx?aid=56080898 ER -