TY  - CHAP
M1  - Book, Section
TI  - Chapter 163. Cutaneous Necrotizing Venulitis
A1  - Soter, Nicholas A.
A2  - Goldsmith, Lowell A.
A2  - Katz, Stephen I.
A2  - Gilchrest, Barbara A.
A2  - Paller, Amy S.
A2  - Leffell, David J.
A2  - Wolff, Klaus
PY  - 2012
T2  - Fitzpatrick's Dermatology in General Medicine, 8e
AB  - |PrintCutaneous  Necrotizing  Venulitis  at  a  GlanceSignature  lesions  are  erythematous  papules  that  do  not  blanch  when  the  skin  is  pressed  and  are  known  as  palpable  purpura.Palpable  purpura  persists  for  1  to  4  weeks  and  resolves  at  times  with  transient  hyperpigmentation  and/or  atrophic  scars.Macules,  papules,  urticaria/angioedema,  pustules,  vesicles,  ulcers,  necrosis,  and  livedo  reticularis  also  may  be  present.May  be  characterized  by  episodes  of  recurrent  and  chronic  urticaria  and  angioedema.Lesions  may  occur  anywhere  on  the  skin  but  are  most  common  on  the  lower  extremities  or  over  dependent  areas  such  as  the  back  and  gluteal  regions.May  be  associated  with  connective-tissue  diseases,  notably  rheumatoid  arthritis,  Sjögren  syndrome,  systemic  lupus  erythematous,  and  hypergammaglobulinemic  purpura.There  may  be  many  precipitating  causes  but  infections  and  drugs  are  most  common.The  most  widely  recognized  subgroup  of  idiopathic  cutaneous  necrotizing  vasculitis  in  children  is  Henoch–Schönlein  purpura.Histopathologic  criteria  include  necrosis  of  the  blood  vessels  with  the  ‘deposition  of  fibrinoid  material  and  dermal  cellular  infiltrates  that  consist  of  neutrophils  with  nuclear  debris,  mononuclear  cells,  and  extravasated  erythrocytes.  
SN  - 
PB  - The McGraw-Hill Companies
CY  - New York, NY
Y2  - 2024/04/19
UR  - accessmedicine.mhmedical.com/content.aspx?aid=56078348
ER  -