TY - CHAP M1 - Book, Section TI - Chapter 161. Sjögren's Syndrome A1 - Illei, Gabor A1 - Danielides, Stamatina A2 - Goldsmith, Lowell A. A2 - Katz, Stephen I. A2 - Gilchrest, Barbara A. A2 - Paller, Amy S. A2 - Leffell, David J. A2 - Wolff, Klaus PY - 2012 T2 - Fitzpatrick's Dermatology in General Medicine, 8e AB - |PrintSjögren's Syndrome at a GlanceChronic autoimmune disease characterized by chronic inflammation involving the exocrine glands.Salivary and lachrymal glands are predominantly affected leading to dry mouth and dry eyes.May occur alone (primary Sjögren's syndrome), or may coexist with other systemic connective tissue disorders (secondary Sjögren's syndrome).Systemic manifestations, such as fatigue, arthritis, vasculitis, interstitial pulmonary disease, peripheral or central neuropathy, and autonomic nervous dysfunction may accompany glandular involvement.Patients with systemic manifestations are at higher risk of lymphoma.Treatment of sicca symptoms is mainly symptomatic, whereas management of extraglandular manifestations is similar to other autoimmune diseases. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/19 UR - accessmedicine.mhmedical.com/content.aspx?aid=56077702 ER -