TY - CHAP M1 - Book, Section TI - Chapter 74. Vitiligo A1 - Birlea, Stanca A. A1 - Spritz, Richard A. A1 - Norris, David A. A2 - Goldsmith, Lowell A. A2 - Katz, Stephen I. A2 - Gilchrest, Barbara A. A2 - Paller, Amy S. A2 - Leffell, David J. A2 - Wolff, Klaus PY - 2012 T2 - Fitzpatrick's Dermatology in General Medicine, 8e AB - |PrintVitiligo at a GlanceThe most frequent depigmenting disorder, affecting 0.3%–0.5% of the population worldwideAn acquired disease involving multiple genes and nongenetic environmental factorsCharacterized by progressive autoimmune-mediated destruction of epidermal melanocytesTypical presentation: patches of white skin and hairCause of physiological and social stigma among affected individualsIncreased risk for other autoimmune diseases, unpredictable evolution and unsatisfactory therapeutic outcomes SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/19 UR - accessmedicine.mhmedical.com/content.aspx?aid=56043354 ER -