TY - CHAP M1 - Book, Section TI - Chapter 50. Hemodialysis A1 - Rocco, Michael V. A1 - Moossavi, Shahriar A2 - Lerma, Edgar V. A2 - Berns, Jeffrey S. A2 - Nissenson, Allen R. PY - 2009 T2 - CURRENT Diagnosis & Treatment: Nephrology & Hypertension AB - The major forces responsible for solute transport across the membrane are diffusion and convection. Diffusion is influenced by the concentration gradient of the solute, the solute characteristics (eg, molecular weight and charge), and the membrane characteristics (eg, pore size and number). Removal of solutes by diffusion is enhanced by a large concentration gradient, small solute size, and a membrane with a large surface area and many large pores. The concentration gradient is maximized by using countercurrent flow of blood and dialysate. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/19 UR - accessmedicine.mhmedical.com/content.aspx?aid=6340414 ER -