TY  - CHAP
M1  - Book, Section
TI  - Chapter 25. Focal Segmental Glomerulosclerosis
A1  - Gipson, Debbie S.
A1  - Trachtman, Howard
A2  - Lerma, Edgar V.
A2  - Berns, Jeffrey S.
A2  - Nissenson, Allen R.
PY  - 2009
T2  - CURRENT Diagnosis & Treatment: Nephrology & Hypertension
AB  - Focal  segmental  glomerulosclerosis  (FSGS)  can  be  primary  or  secondary.Diagnosis  requires  the  presence  of  the  characteristic  histopathologic  lesion.Genetic  abnormalities  in  podocyte  proteins  may  account  for  25%  of  primary  FSGS.The  presenting  complaint  is  usually  proteinuria  or  nephrotic  syndrome.Nearly  50%  of  cases  progress  to  end-stage  renal  disease  (ESRD)  over  5–10  years  and  disease  recurs  in  30%  of  those  who  receive  a  kidney  transplant.Failure  to  respond  to  corticosteroid  treatment  is  a  poor  prognostic  sign  and  there  is  no  proven  therapy  in  these  patients.  
SN  - 
PB  - The McGraw-Hill Companies
CY  - New York, NY
Y2  - 2024/04/19
UR  - accessmedicine.mhmedical.com/content.aspx?aid=6335662
ER  -