TY - CHAP M1 - Book, Section TI - Chapter 60. Lesions of the Anterior Skull Base A1 - Morris, Luc G. T. A2 - Lalwani, Anil K. PY - 2012 T2 - CURRENT Diagnosis & Treatment in Otolaryngology—Head & Neck Surgery, 3e AB - Neoplasms of the anterior skull base (ASB) continue to challenge skull base surgeons, despite tremendous advances in multidisciplinary management. These lesions represent a diverse group of tumor types located within a surgically treacherous region. Historically, these tumors were considered unresectable. If surgery was attempted, it generally consisted of a lateral rhinotomy which inevitably resulted in incomplete tumor resection and dismal survival outcomes. The first combined neurosurgical and transfacial resections were reported in the mid-1950s, and the craniofacial resection was popularized by Ketcham and colleagues in 1963. Since this time, advances in diagnostic technology, interventional radiology, endoscopic endonasal surgery, and minimally invasive neurosurgery have facilitated the emergence of the young subspecialty of skull base surgery. Contemporary ASB surgical techniques have significantly expanded the limits of technical resectability while consolidating the gains that have been made in reducing morbidity and mortality. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=55772450 ER -