TY  - CHAP
M1  - Book, Section
TI  - Chapter 63. Cerebrovascular Disease
A1  - Aiyagari, Venkatesh
A1  - Powers, William J.
A1  - Diringer, Michael N.
A2  - Hall, Jesse B.
A2  - Schmidt, Gregory A.
A2  - Wood, Lawrence D.H.
PY  - 2005
T2  - Principles of Critical Care, 3e
AB  - Nonarteriosclerotic  causes  of  stroke  occur  more  commonly  in  patients  admitted  to  the  ICU  and  should  be  carefully  sought  by  appropriate  diagnostic  tests.In  patients  with  acute  ischemic  stroke,  reduction  of  systemic  blood  pressure  may  carry  a  risk  of  producing  further  neurologic  deterioration.Intravenous  tissue  plasminogen  activator  improves  outcome  in  carefully  selected  patients  with  acute  ischemic  stroke  when  treatment  is  instituted  within  3  hours  of  onset.Clinical  trials  of  anticoagulation  with  heparin  or  heparin-like  drugs  in  patients  with  acute  cerebral  ischemia  or  infarction  have  shown  no  benefit.  If  other  indications  for  acute  anticoagulation  are  present,  these  drugs  may  be  given  safely.Emergency  neurosurgical  intervention  should  be  strongly  considered  in  patients  with  cerebellar  infarction  or  hemorrhage  and  consequent  brain  stem  compression.Early  surgical  clipping  or  coiling  of  ruptured  aneurysms  removes  the  risk  of  rebleeding  and  facilitates  the  effective  management  of  delayed  vasospasm  and  hydrocephalus.  
SN  - 
PB  - The McGraw-Hill Companies
CY  - New York, NY
Y2  - 2023/05/28
UR  - accessmedicine.mhmedical.com/content.aspx?aid=2292684
ER  -