TY - CHAP M1 - Book, Section TI - Chapter 43. Nonalcoholic Fatty Liver Disease A1 - Cohen, David E. A1 - Anania, Frank A. A2 - Greenberger, Norton J. A2 - Blumberg, Richard S. A2 - Burakoff, Robert PY - 2012 T2 - CURRENT Diagnosis & Treatment: Gastroenterology, Hepatology, & Endoscopy, 2e AB - Nonalcoholic fatty liver disease (NAFLD) is an overarching concept that includes simple steatosis and nonalcoholic steatohepatitis (NASH).NAFLD is commonly associated with the metabolic syndrome, obesity, diabetes, and hyperlipidemia; 80% of patients with the metabolic syndrome have NAFLD.Patients generally present without clinical symptoms but with mild transaminase elevations; NAFLD is the most common cause of increased serum transaminase levels.NAFLD is a clinical diagnosis after exclusion of other causes of liver disease.Ultrasound, computed tomography, and magnetic resonance imaging are useful for the detection.Liver biopsy is currently required to distinguish NASH from NAFLD. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/25 UR - accessmedicine.mhmedical.com/content.aspx?aid=55961163 ER -