TY - CHAP M1 - Book, Section TI - Multiple Sclerosis A1 - Douglas, Vanja C. A1 - Aminoff, Michael J. A2 - Papadakis, Maxine A. A2 - Rabow, Michael W. A2 - McQuaid, Kenneth R. A2 - Gandhi, Monica PY - 2025 T2 - Current Medical Diagnosis & Treatment 2025 AB - Key Clinical Updates in Multiple SclerosisPatients without a typical clinical attack may be diagnosed with radiologically isolated syndrome if a brain MRI incidentally demonstrates findings consistent with multiple sclerosis. Teriflunomide and dimethyl fumarate were shown to delay time to first clinical attack compared to placebo in such patients.Lebrun-Frénay C et al. JAMA Neurol. [PMID: 37603328]Okuda DT et al. Ann Neurol. [PMID: 36401339] SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2025/07/12 UR - accessmedicine.mhmedical.com/content.aspx?aid=1209237595 ER -