TY - CHAP M1 - Book, Section TI - Pulmonary Diseases Due to Nontuberculous Mycobacteria A1 - Albin, John S. A1 - Hurtado, Rocio M. A2 - Grippi, Michael A. A2 - Antin-Ozerkis, Danielle E. A2 - Dela Cruz, Charles S. A2 - Kotloff, Robert M. A2 - Kotton, Camille Nelson A2 - Pack, Allan I. PY - 2023 T2 - Fishman’s Pulmonary Diseases and Disorders, 6e AB - This chapter focuses on the diagnosis and management of pulmonary infections caused by nontuberculous mycobacteria (NTM), a large group of species of the genus Mycobacterium that can cause disease in humans and that are distinct from other classic mycobacterial pathogens, such as M. leprae, M. ulcerans, and species of the M. tuberculosis complex. Despite the diversity of this group of pathogens, the clinical presentation and diagnostic approach to most pulmonary NTM infections is similar, and the vast majority of disease is caused by a handful of species, including those of the M. avium (MAC) and M. abscessus (MAb) complexes, as well as M. kansasii and M. xenopi. Management differs according to species, extent of disease, and susceptibility patterns. We describe here the epidemiology and pathogenesis of pulmonary NTM infections and a general diagnostic approach. We then proceed to the treatment regimens used for common NTMs and discuss the nuances associated with management in special populations. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/16 UR - accessmedicine.mhmedical.com/content.aspx?aid=1195015460 ER -