TY  - CHAP
M1  - Book, Section
TI  - Immunosuppressants, Immunomodulation, and Tolerance
A1  - Rothlin, Carla V.
A1  - Gutkind, J. Silvio
A2  - Brunton, Laurence L.
A2  - Knollmann, Björn C.
PY  - 2023
T2  - Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 14th Edition
AB  - This  chapter  reviews  the  components  of  the  immune  response  and  drugs  that  modulate  immunity  via  immunosuppression,  tolerance,  or  neutralization  of  cytokine  signaling.  Four  major  classes  of  immunosuppressive  drugs  are  discussed:  glucocorticoids,  calcineurin  inhibitors,  antiproliferative  and  antimetabolic  agents,  and  antibodies  or  small  molecules  that  target  cytokine  signaling.  While  there  are  similarities,  the  approach  to  the  use  of  immunosuppressant  drugs  in  transplant  rejection  has  evolved  separately  from  the  approaches  used  to  treat  autoimmune  disease  and  thus  is  presented  separately.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1193234400
ER  -