TY - CHAP M1 - Book, Section TI - Mechanisms of Arrhythmias A1 - Kiefer, Todd A1 - Granger, Christopher B. A1 - Jackson, Kevin P. A2 - Papadakis, Maxine A. A2 - McPhee, Stephen J. A2 - Rabow, Michael W. A2 - McQuaid, Kenneth R. PY - 2023 T2 - Current Medical Diagnosis & Treatment 2023 AB - Susceptibility to arrhythmias may result from genetic abnormalities or acquired structural heart disease. Susceptibility may be increased by electrolyte abnormalities, hormonal imbalances (thyrotoxicosis, hypercatecholaminergic states), hypoxia, medication effects (such as QT interval prolongation or changes in automaticity, conduction, and refractoriness), and myocardial ischemia. Ongoing research has provided important information on the genetic basis of arrhythmias and knowledge in this arena is expanding rapidly. Most arrhythmias can be classified as (1) disorders of impulse formation or automaticity, (2) abnormalities of impulse conduction, (3) reentry, and (4) triggered activity. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/24 UR - accessmedicine.mhmedical.com/content.aspx?aid=1193147651 ER -