TY - CHAP M1 - Book, Section TI - Preterm Labor A1 - Rogers, Vanessa L. A1 - Roberts, Scott W. A2 - Papadakis, Maxine A. A2 - McPhee, Stephen J. A2 - Rabow, Michael W. A2 - McQuaid, Kenneth R. PY - 2023 T2 - Current Medical Diagnosis & Treatment 2023 AB - Key Clinical Updates in Preterm LaborThe recommended regimen for antimicrobial prophylaxis against group B streptococcus is penicillin G, 5 million units intravenously as a loading dose and then 2.5–3 million units intravenously every 4 hours until delivery. In penicillin-allergic patients not at high risk for anaphylaxis, 2 g of cefazolin can be given intravenously as an initial dose and then 1 g intravenously every 8 hours until delivery. In patients at high risk for anaphylaxis, vancomycin, 20 mg/kg intravenously every 8 hours until delivery, can be used. Clindamycin, 900 mg intravenously every 8 hours until delivery, can also be used after a group B streptococcal isolate has been confirmed to be susceptible to clindamycin.American College of Obstetricians and Gynecologists. Obstet Gynecol. [PMID: 34794160] SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/17 UR - accessmedicine.mhmedical.com/content.aspx?aid=1193159382 ER -