TY - CHAP M1 - Book, Section TI - Cirrhosis A1 - Friedman, Lawrence S. A2 - Papadakis, Maxine A. A2 - McPhee, Stephen J. A2 - Rabow, Michael W. A2 - McQuaid, Kenneth R. PY - 2023 T2 - Current Medical Diagnosis & Treatment 2023 AB - Key Clinical Updates in CirrhosisIn patients with clinically significant portal hypertension, carvedilol, a nonselective beta receptor antagonist with alpha-1 blocking activity, appears to reduce the frequency of decompensating events, although it may lead to hypotension particularly in patients with decompensated cirrhosis.Tandon P et al. Clin Gastroenterol Hepatol. [PMID: 33221550]Vancomycin should be added in patients with prior bacterial peritonitis or a positive surveillance swab for methicillin-resistant Staphylococcus aureus. Daptomycin should be added in patients with a positive surveillance swab for vancomycin-resistant enterococcus. Meropenem can be used in patients with current or recent exposure to piperacillin-tazobactam.Biggins SW et al. Hepatology. [PMID: 33942342] SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accessmedicine.mhmedical.com/content.aspx?aid=1193152539 ER -