TY  - CHAP
M1  - Book, Section
TI  - Renal Amyloidosis
A1  - Dirkx, Tonja C.
A1  - Woodell, Tyler B.
A2  - Papadakis, Maxine A.
A2  - McPhee, Stephen J.
A2  - Rabow, Michael W.
A2  - McQuaid, Kenneth R.
PY  - 2023
T2  - Current Medical Diagnosis & Treatment 2023
AB  - Amyloidosis  is  a  relatively  rare  cause  of  nephrotic  syndrome.  It  is  caused  by  tissue  deposition  of  an  overproduced  and  abnormally-folded  protein  (amyloid).  Several  different  proteins  can  form  amyloid  fibrils  with  renal  deposition.  Primary  amyloidosis,  or  AL  amyloidosis,  is  the  most  common  form  and  is  due  to  a  plasma  cell  dyscrasia  causing  overproduction  and  deposition  of  monoclonal  Ig  light  chains  (see  Chapter  13).  Secondary  amyloidosis,  or  AA  amyloidosis,  can  rarely  occur  in  chronic  inflammatory  disease  such  as  rheumatoid  arthritis,  IBD,  or  chronic  infection;  in  these  cases,  there  is  deposition  of  an  acute  phase  reactant,  serum  amyloid  A  protein.  Other  less  common  forms  of  amyloidosis  may  also  be  encountered.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/18
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1193127645
ER  -