TY - CHAP M1 - Book, Section TI - Enterococcal Infections A1 - Boslett, Bryn A. A1 - Bystritsky, Rachel A2 - Papadakis, Maxine A. A2 - McPhee, Stephen J. A2 - Rabow, Michael W. A2 - McQuaid, Kenneth R. PY - 2023 T2 - Current Medical Diagnosis & Treatment 2023 AB - Two species, Enterococcus faecalis and Enterococcus faecium, are responsible for most human enterococcal infections. Enterococci cause wound infections, UTIs, bacteremia, and endocarditis. Infections caused by penicillin-susceptible strains should be treated with ampicillin 2 g every 4 hours or penicillin 3–4 million units every 4 hours; if the patient is penicillin-allergic, vancomycin 15 mg/kg every 12 hours intravenously can be given. If the patient has endocarditis or meningitis, gentamicin 1 mg/kg every 8 hours intravenously should be added to the regimen for a duration of 2–3 weeks in order to achieve bactericidal activity. In cases of endocarditis, ceftriaxone 2 g every 12 hours may be given instead of gentamicin in combination with the ampicillin, for a duration of 6 weeks. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1193136285 ER -