TY  - CHAP
M1  - Book, Section
TI  - Pulmonary Hypertension
A1  - Maron, Bradley A.
A1  - Loscalzo, Joseph
A2  - Loscalzo, Joseph
A2  - Fauci, Anthony
A2  - Kasper, Dennis
A2  - Hauser, Stephen
A2  - Longo, Dan
A2  - Jameson, J. Larry
PY  - 2022
T2  - Harrison's Principles of Internal Medicine, 21e
AB  - Pulmonary  hypertension  (PH)  is  a  heterogenous  disease  involving  pathogenic  remodeling  of  the  pulmonary  vasculature,  which  increases  pulmonary  artery  pressure  and  vascular  resistance.  The  most  common  causes  of  PH  are  left  heart  or  primary  lung  disease;  PH  is  also  observed  in  some  patients  as  a  late  complication  of  luminal  pulmonary  embolism.  Pulmonary  arterial  hypertension  (PAH)  is  an  uncommon,  but  distinct,  PH  subtype  characterized  by  the  interplay  between  molecular  and  genetic  events  that  cause  an  obliterative  arteriopathy  and  symptoms  of  dyspnea,  chest  pain,  and  syncope.  If  left  untreated,  PH  carries  a  high  mortality  rate,  largely  owing  to  decompensated  right  heart  failure.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/23
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1190498908
ER  -