TY - CHAP M1 - Book, Section TI - Disorders of the Autonomic Nervous System A1 - Barohn, Richard J. A1 - Engstrom, John W. A2 - Loscalzo, Joseph A2 - Fauci, Anthony A2 - Kasper, Dennis A2 - Hauser, Stephen A2 - Longo, Dan A2 - Jameson, J. Larry PY - 2022 T2 - Harrison's Principles of Internal Medicine, 21e AB - The autonomic nervous system (ANS) innervates the entire neuraxis and influences all organ systems. It regulates blood pressure (BP); heart rate; sleep; and glandular, pupillary, bladder, and bowel function. It maintains organ homeostasis and operates automatically; its full importance becomes recognized only when ANS function is compromised, resulting in dysautonomia. Dysautonomia can result from a primary disorder of the central or peripheral nervous system, or from a nonneurogenic cause. Not infrequently more than one contributor may be present, for example the additive effects of a medication in a patient with diabetes mellitus, cardiovascular insufficiency, or normal aging may be responsible. It is helpful to characterize dysautonomia by its time course (acute, subacute, or chronic; progressive or static), severity, and whether manifestations are continuous or intermittent. Hypothalamic disorders that cause disturbances in homeostasis are discussed in Chaps. 18 and 378. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accessmedicine.mhmedical.com/content.aspx?aid=1199143923 ER -