TY  - CHAP
M1  - Book, Section
TI  - Relapsing Polychondritis
A1  - Langford, Carol A.
A2  - Loscalzo, Joseph
A2  - Fauci, Anthony
A2  - Kasper, Dennis
A2  - Hauser, Stephen
A2  - Longo, Dan
A2  - Jameson, J. Larry
PY  - 2022
T2  - Harrison's Principles of Internal Medicine, 21e
AB  - Relapsing  polychondritis  is  an  uncommon  disorder  of  unknown  cause  characterized  by  inflammation  of  cartilage  predominantly  affecting  the  ears,  nose,  and  laryngotracheobronchial  tree.  Multisystem  disease  occurs  commonly  and  can  also  involve  noncartilaginous  tissues  and  organs.  Relapsing  polychondritis  has  been  estimated  to  have  an  annual  incidence  of  3.5  per  million.  The  peak  age  of  onset  is  between  40  and  50  years,  but  the  disease  can  be  seen  in  all  ages  with  both  sexes  being  equally  affected.  Approximately  30%  of  patients  with  relapsing  polychondritis  will  have  another  rheumatologic  disorder,  most  frequently  systemic  vasculitis,  rheumatoid  arthritis,  or  systemic  lupus  erythematosus  (SLE).  Nonrheumatic  disorders  have  also  been  associated  with  relapsing  polychondritis  (Table  366-1).  In  most  cases,  these  disorders  antedate  the  appearance  of  relapsing  polychondritis,  usually  by  months  or  years;  however,  in  other  instances,  the  onset  of  relapsing  polychondritis  can  accompany  disease  presentation.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1198714645
ER  -