TY  - CHAP
M1  - Book, Section
TI  - Neoplasms of the Lung
A1  - Horn, Leora
A1  - Iams, Wade T.
A2  - Loscalzo, Joseph
A2  - Fauci, Anthony
A2  - Kasper, Dennis
A2  - Hauser, Stephen
A2  - Longo, Dan
A2  - Jameson, J. Larry
PY  - 2022
T2  - Harrison's Principles of Internal Medicine, 21e
AB  - Lung  cancer,  which  was  rare  before  1900  with  fewer  than  400  cases  described  in  the  medical  literature,  is  considered  a  disease  of  modern  man,  killing  over  three  times  as  many  men  as  prostate  cancer  and  nearly  twice  as  many  women  as  breast  cancer.  Although  lung  cancer  remains  the  number  one  cause  of  cancer-related  mortality,  a  decline  in  lung  cancer  deaths  has  emerged,  attributed  to  improvements  in  testing  and  therapeutic  strategies  and  a  decline  in  tobacco  usage.  Tobacco  consumption  is  the  primary  cause  of  lung  cancer,  a  reality  firmly  established  in  the  mid-twentieth  century  and  codified  with  the  release  of  the  U.S.  Surgeon  General’s  1964  report  on  the  health  effects  of  tobacco  smoking.  Following  the  report,  cigarette  use  started  to  decline  in  North  America  and  parts  of  Europe,  and  with  it,  so  did  the  incidence  of  lung  cancer.  Although  tobacco  smoking  remains  the  primary  cause  of  lung  cancer  worldwide,  approximately  60%  of  new  lung  cancers  in  the  United  States  occur  in  former  smokers  (smoked  ≥100  cigarettes  per  lifetime,  quit  ≥1  year),  many  of  whom  quit  decades  ago,  or  never  smokers  (smoked  <100  cigarettes  per  lifetime).  Moreover,  one  in  five  women  and  one  in  12  men  diagnosed  with  lung  cancer  have  never  smoked.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/24
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1207536706
ER  -