TY - CHAP M1 - Book, Section TI - Antifungal Drugs A1 - Stringer, Janet L. PY - 2022 T2 - Basic Concepts in Pharmacology: What You Need to Know for Each Drug Class, 6e AB - Fungi are eukaryotes, making it challenging to target the pathogen without significant host toxicity. In addition, many fungal infections occur in poorly vascularized tissues or avascular structures such as the superficial layer of the skin, nails, and hair. Fungi are slow growing and are, therefore, more difficult to kill than bacteria, where cell division can be a target. Because many fungi are opportunistic, host factors play an important role in determining prognosis. The antifungal agents essentially assist the host immune system with the fight against the fungus. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accessmedicine.mhmedical.com/content.aspx?aid=1187634260 ER -