TY  - CHAP
M1  - Book, Section
TI  - Methods in Clinical Coagulation
A1  - Laposata, Michael
A1  - McCaffrey, Peter
PY  - 2022
T2  - Clinical Laboratory Methods: Atlas of Commonly Performed Tests
AB  - A  patient’s  platelet-poor  plasma  (it  is  specifically  plasma  and  not  serum,  as  the  process  of  clotting  plasma  to  create  serum  consumes  the  coagulation  factors)  is  placed  in  a  testing  chamber.  For  the  PT  assay,  the  specimen  is  mixed  with  thromboplastin  and  calcium.  For  the  PTT  assay,  partial  thromboplastin,  an  activator  to  initiate  the  clotting  cascade,  and  calcium  are  added.  The  end  point  of  the  reaction  is  clot  formation  which  may  be  detected  optically,  because  the  sample  becomes  more  turbid  with  clotting,  or  mechanically,  because  clot  formation  reduces  the  ability  of  a  magnet  or  other  movable  object  added  to  move  freely.  
SN  - 
PB  - McGraw Hill, LLC
CY  - New York, NY
Y2  - 2024/04/19
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1187001199
ER  -