TY  - CHAP
M1  - Book, Section
TI  - Antiviral Drugs
A1  - Levinson, Warren
A1  - Chin-Hong, Peter
A1  - Joyce, Elizabeth A.
A1  - Nussbaum, Jesse
A1  - Schwartz, Brian
PY  - 2022
T2  - Review of Medical Microbiology & Immunology: A Guide to Clinical Infectious Diseases, 17e
AB  - Compared  with  the  number  of  drugs  available  to  treat  bacterial  infections,  the  number  of  antiviral  drugs  is  relatively  small.  The  major  reason  for  this  difference  is  the  difficulty  in  obtaining  selective  toxicity  against  viruses;  their  replication  is  intimately  involved  with  the  normal  synthetic  processes  of  the  cell.  Despite  the  difficulty,  several  virus-specific  replication  steps  have  been  identified  that  are  the  site  of  action  of  effective  antiviral  drugs  (Table  35–1).  Table  35–2  describes  the  mode  of  action  of  antiviral  drugs  that  block  early  events  in  viral  replication,  and  Table  35–3  describes  the  mode  of  action  of  antiviral  drugs  that  block  viral  nucleic  acid  synthesis.  Figure  35–1  shows  the  replication  of  a  model  virus  and  the  site  of  action  of  drugs  used  to  treat  various  viral  infections.  Figure  35–2  shows  the  replication  of  human  immunodeficiency  virus  (HIV)  and  the  site  of  action  of  drugs  used  to  treat  HIV  infection.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/16
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1190861784
ER  -