TY - CHAP M1 - Book, Section TI - Prenatal Diagnosis of Genetic Disorders A1 - Pyeritz, Reed E. A2 - Papadakis, Maxine A. A2 - McPhee, Stephen J. A2 - Rabow, Michael W. A2 - McQuaid, Kenneth R. PY - 2022 T2 - Current Medical Diagnosis & Treatment 2022 AB - It is possible to diagnose in utero, before the middle of the second trimester, mendelian disorders for which a gene is associated, all chromosome aberrations, and a number of congenital malformations that are not mendelian. The first step toward prenatal diagnosis is taken when the expecting couple, the primary care provider, or the obstetrician thinks of the need for it. However, even for the most common indication for such service—advanced maternal age—less than 50% of all women 35 years and older in the United States are offered prenatal testing. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1184181682 ER -