TY - CHAP M1 - Book, Section TI - Viral Arthritis A1 - Yazdany, Jinoos A1 - Manno, Rebecca L. A2 - Papadakis, Maxine A. A2 - McPhee, Stephen J. A2 - Rabow, Michael W. A2 - McQuaid, Kenneth R. PY - 2022 T2 - Current Medical Diagnosis & Treatment 2022 AB - Arthralgias occur frequently in the course of acute infections with many viruses, but frank arthritis is uncommon with the notable exceptions of acute parvovirus B19 infection and Chikungunya fever. Parvovirus B19 causes an acute polyarthritis in 50–60% of adult cases (infected children develop the febrile exanthem known as “slapped cheek fever”). The arthritis can mimic rheumatoid arthritis but is almost always self-limited and resolves within several weeks. The diagnosis is established by the presence of IgM antibodies specific for parvovirus B19. Chikungunya fever is an arthropod-borne viral infection that is endemic to West Africa but has spread to multiple locations including the Indian Ocean islands, the Caribbean and Central and Latin America. Clinical manifestations include high fever, rash, and incapacitating bone pain. Acute polyarthralgia and polyarthritis are common and can persist for months or years. For Chikungunya-associated chronic arthritis, treatment with methotrexate or other DMARD agents may be an option. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/18 UR - accessmedicine.mhmedical.com/content.aspx?aid=1184193562 ER -