TY - CHAP M1 - Book, Section TI - Hemochromatosis A1 - Friedman, Lawrence S. A2 - Papadakis, Maxine A. A2 - McPhee, Stephen J. A2 - Rabow, Michael W. A2 - McQuaid, Kenneth R. PY - 2022 T2 - Current Medical Diagnosis & Treatment 2022 AB - ESSENTIALS OF DIAGNOSISUsually suspected because of a family history or an elevated iron saturation or serum ferritin.Most patients are asymptomatic; the disease is rarely recognized clinically before the fifth decade.Hepatic abnormalities and cirrhosis, heart failure, hypogonadism, and arthritis.HFE gene mutation (usually C282Y/C282Y) is found in most cases. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/18 UR - accessmedicine.mhmedical.com/content.aspx?aid=1184173570 ER -