TY - CHAP M1 - Book, Section TI - Leukemias & Other Myeloproliferative Neoplasms A1 - Damon, Lloyd E. A1 - Andreadis, Charalambos Babis A2 - Papadakis, Maxine A. A2 - McPhee, Stephen J. A2 - Rabow, Michael W. A2 - McQuaid, Kenneth R. PY - 2022 T2 - Current Medical Diagnosis & Treatment 2022 AB - Myeloproliferative disorders are due to acquired clonal abnormalities of the hematopoietic stem cell (eFigure 13–19). Since the stem cell gives rise to myeloid, erythroid, and platelet cells, qualitative and quantitative changes are seen in all of these cell lines. Classically, the myeloproliferative disorders produce characteristic syndromes with well-defined clinical and laboratory features (Tables 13–13 and 13–14). However, these disorders are grouped together because they may evolve from one into another and because hybrid disorders are commonly seen. All of the myeloproliferative disorders may progress to AML. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/24 UR - accessmedicine.mhmedical.com/content.aspx?aid=1184165978 ER -