TY - CHAP M1 - Book, Section TI - Pathology of Lymphomas A1 - Gonzalez, Blanca A1 - Wang, Luojun A1 - Campo, Elias A2 - Kaushansky, Kenneth A2 - Prchal, Josef T. A2 - Burns, Linda J. A2 - Lichtman, Marshall A. A2 - Levi, Marcel A2 - Linch, David C. PY - 2021 T2 - Williams Hematology, 10e AB - SUMMARYThe World Health Organization (WHO) classification of the lymphocytic neoplasms updated in 2016/2017 represents a worldwide consensus on lymphoma diagnosis and is based on two major principles: the stratification of neoplasms according to their cell lineage and their derivation from precursor or mature cells.* The classification recognizes specific diseases based on a combination of morphology; immunophenotype; and genetic, molecular, and clinical features. The WHO classification identifies three main groups of lymphoid malignancies: B-cell neoplasms, T- and natural killer (NK)-cell neoplasms, and Hodgkin lymphoma. In addition to well-defined entities, the classification includes some provisional entities that correspond to categories for which there was insufficient evidence to support its recognition as distinct diseases and borderline categories with overlapping features between large B-cell lymphomas and Burkitt or Hodgkin lymphoma. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1180447769 ER -