TY - CHAP M1 - Book, Section TI - Prevention of Infective Endocarditis A1 - Cohn, Steven L. A2 - Cohn, Steven L. PY - 2021 T2 - Decision Making in Perioperative Medicine: Clinical Pearls AB - Infective endocarditis (IE) is thought to result from formation of nonbacterial thrombotic endocarditis (platelets and fibrin) on the surface of a valve or damaged endothelial surface, bacteremia with adherence to the fibrin-platelet matrix, and proliferation of the bacteria within the vegetation. The annual incidence of IE has been increasing from 2000 to 2011 and ranges from 3 to 10 episodes/100,000 population worldwide and 11 to 15/100,000 in the U.S. with a male predominance. Incidence of native-valve IE has decreased, while IE related to prosthetic valves and cardiac devices has increased. SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/04/25 UR - accessmedicine.mhmedical.com/content.aspx?aid=1179530699 ER -