TY - CHAP M1 - Book, Section TI - Antiphospholipid Syndrome A1 - Gkrouzman, Elena A1 - Erkan, Doruk A2 - Stone, John H. PY - 2021 T2 - Current Diagnosis & Treatment: Rheumatology, 4e AB - Persistent antiphospholipid antibodies (lupus anticoagulant test, anticardiolipin [aCL] antibodies, and anti–β2-glycoprotein-I antibodies [aβ2GPI]) measureable in the peripheral blood.Arterial and venous thrombosis affecting the micro- and/or macro-vasculature.Pregnancy morbidity, including pregnancy losses beyond the first trimester.Nonthrombotic manifestations such as thrombocytopenia or cardiac valve disease.Wide spectrum of manifestations including multiple organ thromboses (catastrophic antiphospholipid syndrome).Traditional thrombosis and cardiovascular disease risk factors also contribute to clinical events. SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/04/18 UR - accessmedicine.mhmedical.com/content.aspx?aid=1180196688 ER -