TY - CHAP M1 - Book, Section TI - Autoimmune Bullous Diseases A1 - Hardin, J. Matthew A2 - Knoop, Kevin J. A2 - Stack, Lawrence B. A2 - Storrow, Alan B. A2 - Thurman, R. Jason PY - 2021 T2 - The Atlas of Emergency Medicine, 5e AB - Autoimmune bullous diseases are uncommon but have dramatic presentations. Bullous pemphigoid (BP) results from autoantibodies to the epidermal basement membrane and creates tense bullae, frequently located on the proximal extremities. In pemphigus vulgaris (PV), the autoantibodies are directed against the epidermal keratinocytes. This results in flaccid bullae (more superficial bullae that easily slough off to form erosions). The delicate bullae and subsequent erosions of PV commonly present in the pharynx, scalp, and trunk. Paraneoplastic pemphigus presents with severe oral ulcerations (like SJS/TEN; see related item) and resolves with treatment of the associated malignancy. SN - PB - McGraw-Hill CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1181043790 ER -