TY - CHAP M1 - Book, Section TI - Scarlet Fever (Scarlatina) A1 - Shah, Ashish A1 - Sobolewski, Brad A1 - Mittiga, Matthew R. A2 - Knoop, Kevin J. A2 - Stack, Lawrence B. A2 - Storrow, Alan B. A2 - Thurman, R. Jason PY - 2021 T2 - The Atlas of Emergency Medicine, 5e AB - Scarlet fever manifests as diffuse blanching “sandpaper-like” erythematous macules and papules caused by erythrogenic toxin production from group A β-hemolytic Streptococcus pharyngitis. Occasionally, the site of infection is skin (impetigo) or perianal. The disease usually occurs in children 2 to 10 years of age. The typical presentation of scarlet fever includes fever, headache, sore throat, nausea, vomiting, and malaise followed by the characteristic scarlatiniform rash. The rash initially occurs on the groin and trunk, spreading to the face (often with perioral sparing) and neck, then quickly becomes generalized. Desquamation occurs after 5 to 7 days. On the tongue, a thick, white coat and swollen papillae may be seen (“strawberry tongue”). Palatal petechiae and tender anterior cervical lymphadenopathy may be present. The gold standard for diagnosis is a positive throat culture of a swab from the tonsillar pillars, though rapid antigen testing is highly specific and can provide prompt diagnosis. The differential diagnosis includes enteroviral infections, staphylococcal scalded skin syndrome, viral hepatitis, infectious mononucleosis, toxic shock syndrome, drug eruptions, rubella, mercury poisoning, and Kawasaki disease. SN - PB - McGraw-Hill CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1181044452 ER -