TY - CHAP M1 - Book, Section TI - Anticoagulation A1 - Rajasekhar, Anita A1 - Beyth, Rebecca J. A2 - Walter, Louise C. A2 - Chang, Anna A2 - Chen, Pei A2 - Harper, G. Michael A2 - Rivera, Josette A2 - Conant, Rebecca A2 - Lo, Daphne A2 - Yukawa, Michi PY - 2021 T2 - Current Diagnosis & Treatment Geriatrics, 3e AB - Anticoagulants are a class of drugs essential for the optimal management of many thromboembolic and vascular disorders that are highly prevalent among older patients. Anticoagulants are unique compared to most pharmacologic agents because even small deviations from “therapeutic levels” place patients at risk for life-threatening complications. While older patients with multimorbidity are particularly susceptible to thrombosis, they also have higher risks of bleeding than the general population. With the approval of direct oral anticoagulants (DOACs) for thrombotic conditions, these agents are being used more frequently than traditional anticoagulants in the older patient due to convenience and lower bleeding risk in the general population. This chapter briefly reviews current anticoagulant therapy and focuses on the newer agents and recommendations for their use in older patients. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/25 UR - accessmedicine.mhmedical.com/content.aspx?aid=1180016813 ER -