TY - CHAP M1 - Book, Section TI - Screening for Prostate Cancer A1 - Ozambela, Manuel A1 - Preston, Mark A. A2 - Bhasin, Shalender A2 - O’Leary, Michael P. A2 - Basaria, Shehzad S. PY - 2021 T2 - Essentials of Men’s Health AB - Identifying healthy, asymptomatic individuals harboring occult cancer before it becomes symptomatic intuitively makes sense, assuming that disease progresses in a linear fashion; at first silent and later progressing through states of increasing abnormality, until it becomes symptomatic and, eventually, lethal. In 1907, Dr. Charles Childe published his book, The Control of a Scourge, Or, How Cancer Is Curable. His argument was that the mortality associated with cancer was related to its late presentation: “Cancer itself is not incurable … it is the delay that makes it so.” This thesis informed the inception of cancer screening in the medical community and, with it, the aspiration of finding disease at an earlier stage when intervention may be curative, or at least curtail morbidity. SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/04/19 UR - accessmedicine.mhmedical.com/content.aspx?aid=1174516447 ER -