TY - CHAP M1 - Book, Section TI - Adaptive Immunity: T-Cell–Mediated Immunity A1 - Levinson, Warren A1 - Chin-Hong, Peter A1 - Joyce, Elizabeth A. A1 - Nussbaum, Jesse A1 - Schwartz, Brian PY - 2020 T2 - Review of Medical Microbiology & Immunology: A Guide to Clinical Infectious Diseases, 16e AB - Innate immunity (see Chapter 58) and antibodies (see Chapter 61) are important mechanisms for preventing infections from taking hold, but in many infectious diseases, it is primarily the T cells that orchestrate resistance and recovery. Furthermore, T cells are important in the immune system’s surveillance for cancer, and they are responsible for most autoimmune diseases and rejection of organ transplants. The strongest evidence for the importance of T cells comes from the increase in infections and cancers that occurs when T-cell function is reduced by immunosuppressive drugs, by acquired diseases such as human immunodeficiency virus (HIV), or in congenital (primary) immunodeficiency syndromes. SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/04/18 UR - accessmedicine.mhmedical.com/content.aspx?aid=1171926408 ER -