TY - CHAP M1 - Book, Section TI - Disorders of Sex Development A1 - Baskin, Laurence S. A2 - McAninch, Jack W. A2 - Lue, Tom F. PY - 2020 T2 - Smith & Tanagho's General Urology, 19e AB - What defines our sexuality is a complex interaction between our genetic makeup, environmental stimulus, and cultural influences. The origins of our sexuality occur at the time of conception when the genetic material from two sources of the opposite sex coalesces into a new individual. From that moment, sexual differentiation occurs by a highly organized process. Sex chromosomes and autosomes dictate the development of gonads; the gonads, in turn, produce hormones, which then direct the development of the internal and external genitalia. Disorders of sex development (DSD) or differentiation arise from abnormalities in chromosomes, gonadal development, or hormonal production/activity. SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/04/16 UR - accessmedicine.mhmedical.com/content.aspx?aid=1171186744 ER -