TY - CHAP M1 - Book, Section TI - Amyloidosis A1 - Jameson, J. Larry A1 - Fauci, Anthony S. A1 - Kasper, Dennis L. A1 - Hauser, Stephen L. A1 - Longo, Dan L. A1 - Loscalzo, Joseph PY - 2020 T2 - Harrison's Manual of Medicine, 20e AB - Amyloidosis is a term for a group of protein misfolding disorders characterized by the extracellular deposition of insoluble polymeric protein fibrils in tissues and organs. Clinical manifestations depend on anatomic distribution and intensity of amyloid protein deposition; they range from local deposition with little significance to involvement of virtually any organ system with severe pathophysiologic consequences. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1167068476 ER -