TY - CHAP M1 - Book, Section TI - Overview: Mycotic Infections A1 - Rose, Stacey R. A1 - Hamill, Richard J. A2 - Papadakis, Maxine A. A2 - McPhee, Stephen J. A2 - Rabow, Michael W. PY - 2020 T2 - Current Medical Diagnosis and Treatment 2020 AB - Fungal infections have assumed an increasingly important role as use of broad-spectrum antimicrobial agents has increased and the number of immunodeficient patients has grown. Some pathogens (eg, Cryptococcus, Candida, Pneumocystis, Fusarium) rarely cause serious disease in immunocompetent hosts. Other endemic fungi (eg, Histoplasma, Coccidioides, Paracoccidioides) commonly cause disease in immunocompetent persons but tend to be more aggressive in immunocompromised ones. Superficial mycoses are discussed in Chapter 6-14. Successful management of most systemic fungal infections requires knowledge of the natural history of these diseases and the specific tests needed to make a diagnosis as well as familiarity with the unique pharmacokinetics, adverse effects, and drug interactions of the various therapeutic agents. Consequently, clinicians with extensive experience in the management of these disorders should be routinely consulted. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2022/05/25 UR - accessmedicine.mhmedical.com/content.aspx?aid=1166620145 ER -