TY - CHAP M1 - Book, Section TI - Allergy Testing A1 - Hellmann, David B. A1 - Imboden Jr., John B. A2 - Papadakis, Maxine A. A2 - McPhee, Stephen J. A2 - Rabow, Michael W. PY - 2020 T2 - Current Medical Diagnosis and Treatment 2020 AB - To maximize the positive predictive value of allergy testing, a positive test result must be correlated with the history. Patients selected for testing include those with moderate to severe disease, those who are potential candidates for allergen immunotherapy, and those with strong predisposing factors for atopic diatheses, eg, a strong family history of atopy or ongoing exposure to potential sources of allergen. Since the development of rhinitis precedes the presentation of asthma in over half of cases, early intervention may decrease the risk of more severe clinical illness. The type of immune response must be consistent with the nature of the disease. For example, IgE antibody causes allergic rhinitis but not allergic contact dermatitis. IgE antibodies are detected by in vivo (skin tests) or in vitro methods. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2022/05/22 UR - accessmedicine.mhmedical.com/content.aspx?aid=1166169912 ER -