TY - CHAP M1 - Book, Section TI - Carcinoma of the Breast in Pregnancy A1 - Rogers, Vanessa L. A1 - Roberts, Scott W. A2 - Papadakis, Maxine A. A2 - McPhee, Stephen J. A2 - Rabow, Michael W. PY - 2020 T2 - Current Medical Diagnosis and Treatment 2020 AB - Carcinoma of the breast (see also Chapter 17-7) is one of the most commonly diagnosed cancers in pregnancy. Although the effects of pregnancy on breast cancer progression are unclear, it has been consistently reported that breast cancers diagnosed during pregnancy are more likely to have higher grade disease with associated nodal involvement when compared with those diagnosed in nonpregnant women. This observation underscores the importance of expeditious evaluation of any breast mass in a pregnant woman. Physiologic breast changes in pregnancy include enlargement and glandular hyperplasia, both of which can limit the radiographic evaluation; however, imaging is essential to characterize any palpable mass. Ultrasound is typically the initial modality of choice in a pregnant woman, but mammography should be performed if needed. Biopsy is then required for any suspicious lesion, and if malignancy is discovered, surgery should not be withheld based on the stage of the pregnancy. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2022/05/17 UR - accessmedicine.mhmedical.com/content.aspx?aid=1166168992 ER -