TY - CHAP M1 - Book, Section TI - Thrombotics and Antithrombotics A1 - Slattery, David E. A1 - Pollack, Jr, Charles V. A2 - Tintinalli, Judith E. A2 - Ma, O. John A2 - Yealy, Donald M. A2 - Meckler, Garth D. A2 - Stapczynski, J. Stephan A2 - Cline, David M. A2 - Thomas, Stephen H. PY - 2020 T2 - Tintinalli's Emergency Medicine: A Comprehensive Study Guide, 9e AB - Antithrombotic therapy (i.e., anticoagulants, antiplatelet agents, and fibrinolytics) is used to treat or reduce the risk of arterial and venous thromboembolic conditions, including acute coronary syndrome, deep venous thrombosis and pulmonary embolism (collectively, venous thromboembolic disease), transient ischemic attack, and ischemic stroke (Table 239-1). Moreover, antithrombotic agents help prevent occlusive vascular events in patients at risk for thrombosis due to atherosclerotic arterial disease, atrial fibrillation, medical illness with immobility, or surgical insult. These agents, however, can cause life-threatening complications, primarily serious or life-threatening hemorrhage. Detailed management strategies for thromboembolic disorders are discussed in their respective chapters (see Chapter 49, “Acute Coronary Syndromes”; Chapter 56, “Venous Thromboembolism Including Pulmonary Embolism”; and Chapter 167, “Stroke Syndromes”). SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/04 UR - accessmedicine.mhmedical.com/content.aspx?aid=1166813100 ER -