TY - CHAP M1 - Book, Section TI - Acute Kidney Injury A1 - Sinert, Richard A1 - Peacock Jr., Peter R. A2 - Tintinalli, Judith E. A2 - Ma, O. John A2 - Yealy, Donald M. A2 - Meckler, Garth D. A2 - Stapczynski, J. Stephan A2 - Cline, David M. A2 - Thomas, Stephen H. PY - 2020 T2 - Tintinalli's Emergency Medicine: A Comprehensive Study Guide, 9e AB - Acute kidney injury (AKI) is the deterioration of renal function over hours or days, resulting in the accumulation of toxic wastes and the loss of internal homeostasis. Definitions based on renal function are listed in Table 88-11-4; AKI is classified using the Risk, Injury, Failure, Loss, and End-Stage Renal Failure (RIFLE),2 the Acute Kidney Injury Network (AKIN),3 and the Kidney Disease: Improving Global Outcomes (KDIGO)4 classifications. These definitions assume that renal function has reached a steady state, which limits their applicability to ED patients with AKI whose renal function may be deteriorating. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accessmedicine.mhmedical.com/content.aspx?aid=1185542696 ER -