TY - CHAP M1 - Book, Section TI - Herpesviruses A1 - Riedel, Stefan A1 - Hobden, Jeffery A. A1 - Miller, Steve A1 - Morse, Stephen A. A1 - Mietzner, Timothy A. A1 - Detrick, Barbara A1 - Mitchell, Thomas G. A1 - Sakanari, Judy A. A1 - Hotez, Peter A1 - Mejia, Rojelio PY - 2019 T2 - Jawetz, Melnick, & Adelberg's Medical Microbiology, 28e AB - The herpesvirus family contains several important human viral pathogens. Clinically, the herpesviruses exhibit a wide spectrum of diseases. Some have an extensive host-cell range, and others have a narrow host-cell range. The outstanding property of herpesviruses is their ability to establish lifelong persistent infections in their hosts and to undergo periodic reactivation. Their frequent reactivation in elderly and immunosuppressed patients causes serious health complications. Curiously, the reactivated infection may be clinically quite different from the disease caused by the primary infection. Herpesviruses possess a large number of genes, some of which have proved to be susceptible to antiviral chemotherapy. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1163282508 ER -