TY - CHAP M1 - Book, Section TI - Chlamydia spp. A1 - Riedel, Stefan A1 - Hobden, Jeffery A. A1 - Miller, Steve A1 - Morse, Stephen A. A1 - Mietzner, Timothy A. A1 - Detrick, Barbara A1 - Mitchell, Thomas G. A1 - Sakanari, Judy A. A1 - Hotez, Peter A1 - Mejia, Rojelio PY - 2019 T2 - Jawetz, Melnick, & Adelberg's Medical Microbiology, 28e AB - Chlamydiae that infect humans are divided into three species, Chlamydia trachomatis, Chlamydia pneumoniae, and Chlamydia psittaci, on the basis of antigenic composition, intracellular inclusions, sulfadiazine susceptibility, and disease production. The separation of the genus Chlamydia into the genera Chlamydia and Chlamydophila remains controversial; in this chapter, the three chlamydiae that are pathogens of humans are considered to be in the genus Chlamydia in keeping with publications that do not support the new taxonomy. Other chlamydiae infect animals but rarely if ever infect humans. All chlamydiae exhibit similar morphologic features, share a common group antigen, and multiply in the cytoplasm of their host cells by a distinctive developmental cycle. The chlamydiae can be viewed as Gram-negative bacteria that lack mechanisms for the production of metabolic energy and cannot synthesize adenosine triphosphate (ATP). This restricts them to an intracellular existence, where the host cell furnishes energy-rich intermediates. Thus, chlamydiae are obligate intracellular pathogens. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accessmedicine.mhmedical.com/content.aspx?aid=1163281195 ER -