TY - CHAP M1 - Book, Section TI - Basal Cell Carcinoma and Basal Cell Nevus Syndrome A1 - Tang, Jean Y. A1 - Epstein, Jr., Ervin H. A1 - Oro, Anthony E. A2 - Kang, Sewon A2 - Amagai, Masayuki A2 - Bruckner, Anna L. A2 - Enk, Alexander H. A2 - Margolis, David J. A2 - McMichael, Amy J. A2 - Orringer, Jeffrey S. PY - 2019 T2 - Fitzpatrick's Dermatology, 9e AB - AT-A-GLANCEBasal cell carcinomas (BCCs) are the most common cancers in humans. All BCCs have mutations activating the Hedgehog signaling pathway.BCCs are caused by exposure to ultraviolet light and are associated with PTCH1 gene mutation in most cases.BCCs are locally destructive and rarely metastatic.BCCs are primarily treated by surgical excision, electrodesiccation and curettage, Mohs micrographic surgery, and topical agents. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/04 UR - accessmedicine.mhmedical.com/content.aspx?aid=1161335298 ER -